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In the early nineties, something extraordinary occurred in the world of medical science. While the massive corporation known as Pfizer Pharmaceuticals had its British scientists working hard at trying to design and create a medication that could be used to treat angina and other forms of pulmonary hypertension, a medication was created by accident and labeled under the name UK-92480.
While UK-92480 was being tested as the potential new medicine that could cure the symptoms of angina (a condition wherein the blood vessels supplying the heart with blood constrict, leading to chest pain and breathlessness) the newly made medication appeared to do little to prevent the pain of angina nor effectively treat its symptoms. Pfizer was on the verge of abandoning the medication until
A peculiar regularity started being reported to them from two-thirds of the males who had undergone trials for UK-92480 - while the medicine had not been effective enough in absolving them of their pulmonary hypertension conditions, it had produced a very unique side effect elsewhere. Two-thirds of these men (mostly of an older age) reported a marked increase in their erectile functioning.
It was found that sildenafil citrate contained in sildenafil tablets was a lot more effective at dilating the blood vessels in the penis than in the coronary arteries as was initially hoped. To ensure this discovery was accurate, senior Pfizer scientist Chris Wayman tested sildenafil tablets on samples of penile tissue from men suffering from the form of impotence known as ED. The effect was massive.
The Food and Drug Administration (FDA), the U.S. regulator, gave its approval for the sildenafil tablets which would initially be marketed under the brand name Viagra in 1998. Prior to the invention of sildenafil tablets, there was no oral form of treatment for erectile dysfunction (ED); the only two options were either a penile injection or prosthetic implant.
The incredible success of Viagra leads to many equally effective generic medications being created that contained the same active ingredients as Viagra in the same amount - sildenafil citrate 100 mg. If you are suffering from ED and cannot afford or do not want to pay the exorbitant costs associated with Viagra, then you should strongly consider looking into purchasing medication such as sildenafil tablets.
The onset of the action of sildenafil tablets is fast, taking between 30 - 60-minute post consumption to kick in for the patient. Their mechanism of action is exactly the same as Viagras too; they work as vasodilators to help open blood vessels contained within the penis.
A healthy man gets an erection when he is sexually stimulated due to his state of arousal triggering nitric oxide to be released into the penis. This triggers cyclic-guanosine monophosphate (cGMP), an enzyme responsible for catalyzing blood flow in the soft muscle tissue of the corpus cavernosum in the penis. This creates rigidity in the soft muscle, causing the penis to achieve a state of erection.
In men with ED, the above process cannot take place as they have a PDE-5 presence that far outweighs the presence of cGMP inside their penis. PDE-5 is the enzyme responsible for subsiding blood flow to the penis in healthy men after sexual intercourse has finished. Sildenafil tablets are effective at treating the symptoms of ED as they inhibit the built-up presence of PDE-5, allowing cGMP to function normally.
With millions of men treating their symptoms of ED around the world with sildenafil tablets since 1998, it comes as no surprise that sildenafil tablets are renowned for its safety to use and very few associated side effects. Some users have reported the following mild and manageable side effects which have ceased after the efficacy of the medication wears off: Headaches, facial flushes, and slight muscle cramps.
Join the sexual revolution and come online to buy your medication at the lowest prices guaranteed. Our superb online pharmacy helps thousands of men overcome their ED every day. We deliver sildenafil tablets to the UK within 2 - 4 working days and to the EU within 5 - 7 working days. Deliveries are done speedily and discreetly; medication is of the highest quality; our customer service is 24-hours a day.